Most skin grafts and flaps in normal hosts heal well. In patients with compromised circulation, this may not be the case.
Patients with diabetes or vascular disease of another etiology and patients who have irradiated tissue are especially exposed to flap or graft involvement. In these patients, hyperbaric oxygen therapy has been shown to be helpful.
Unfortunately, if patients are not identified in time, the initial flap or graft may be lost. Even in these cases, patients can significantly benefit from hyperbaric oxygen therapy to prepare the wound bed for another graft or flap procedure. The procedure then has a greater chance of success after this therapy.