Central retinal artery occlusion (CRAO) is a sudden, painless loss of vision caused by obstruction of the central retinal artery and, although rare, can cause permanent visual loss.

CRAO is the most recently approved indication by the Undersea and Hyperbaric Medicine Society (UHMS) for hyperbaric oxygen therapy. CRAO is caused by obstruction of the central retinal artery and, although it is an infrequent cause of vision loss, it leads to permanent loss of vision. Current treatment for CRAO consists of attempts to reduce intraocular pressure and movement of a potential downstream embolus, eye massage, paracentesis of the anterior chamber, and medications (both eye drops and oral drops). Most modalities have been shown to be ineffective.

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